Silent coat is good for the knocks and will stop panels resonating with road noise, but its only the first step. I don't think I'll be doing much with the sheet metal as its not an issue with the Accord; the doors have strengthening beams in addition to the side impact protection which cuts down on a lot of the resonance. I may still do the doors as a guide for others here, but the problem area seems to be the rear wheelhouse insulators which are not thick or heavy enough to deal with the structure-borne noise - the low frequency grumble.
Wheel arches are being treated with absorbent materials as they need to be light and compressible to fit inside, they stop the higher frequency roar on rougher surfaces.
As for using 4 sheets, more is always better but 25% coverage gets you 90% of the way there, each additional bit will get you a much smaller return. I'm all about doing this cheaply so that anyone with a jack and a screwdriver could do this task for under £30
For the upcoming guides the materials being used are here;
Front wheel arches
http://www.carinsulation.co.uk/product/10mm_engine_bay_insulation
A lightweight, compressible man-made fibre material. Mostly for reducing splash noise, stone chip impact noise and absorbing front tyre roar. But most of it is coming from the back.
Rear wheel arches
The same as the front plus;
http://www.carinsulation.co.uk/product/au3002-2_car_insulation_material
More expensive but very effective, this will be the primary absorber of tyre roar from the rear wheel arches.
Rear wheelhouse insulator
This monster;
http://www.carinsulation.co.uk/product/heavy_layer_felt_laminate_insulation
The picture is no good, its a very heavy rubber membrane backed with some felt to help to decouple it from the body resonances, this will go over the existing materials to boost its performance. You can get 5kg/m2 stuff but as this is adding to what the car has you shouldn't need that much weight (or expense)